Radical cystectomy is major surgery to remove the entire bladder, along with nearby lymph nodes and any adjacent organs that may contain cancer cells, to prevent bladder cancer from spreading. It’s the primary treatment for muscle-invasive bladder cancer, and it may also be recommended for high-risk or recurring non-muscle-invasive cancer that returns after treatments like TURBT (transurethral resection of bladder tumour). As doctors determine how far the cancer has spread, some or all of the urethra and other nearby organs may also be removed.
A urologist may suggest bladder removal surgery in certain situations:
- The bladder tumour has invaded the muscle wall
- Carcinoma in situ (CIS) persists after BCG therapy
- A T1 tumour still persists after BCG therapy
The procedure can be performed on both men and women. In men, organs near the bladder that are often removed include the prostate and the seminal vesicles. In women, a radical cystectomy may also include the removal of the uterus, ovaries, and fallopian tubes. In some cases, parts of the vagina may also be removed.




