Urothelial carcinoma refers to a cancer in the lining of the urinary system. Treatments can differ based on the type of bladder cancer, depending on where the cancer tumours have grown and how far they have spread.
Urothelial carcinoma refers to a cancer in the lining of the urinary system. Treatments can differ based on the type of bladder cancer, depending on where the cancer tumours have grown and how far they have spread.
Approximately 75% of bladder cancers are non-muscle invasive, (NMIBC). That means that the bladder cancer tumour is contained completely within the bladder and has not penetrated the muscle surrounding the bladder. You can find more information here.
When the cancer tumours have grown through the lining of the bladder into or through the bladder muscle, it is called muscle invasive bladder cancer, (MIBC). Approximately 25% of bladder cancer cases are muscle invasive. You can find more information here.
Bladder cancer is considered metastatic or advanced when the cancer has spread from the bladder to other parts of the body such as the lymph nodes, liver, lungs, and bone. Approximately 10-15% of patients are diagnosed at this stage. You can find more information here.
While most urothelial cancers (approximately 90-95%) arise in the bladder, upper tract urothelial cancers (UTUCs) arise in the lining of the kidney, called the renal pelvis, or the ureter, the long, thin tube that connects that kidney to the bladder. You can find more information here.
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